Gene expression profiles of two B-complex disparate, genetically inbred Fayoumi chicken lines that differ in susceptibility to Eimeria maxima
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منابع مشابه
Gene expression profiles of two B-complex disparate, genetically inbred Fayoumi chicken lines that differ in susceptibility to Eimeria maxima.
This study was conducted to compare the gene expression profiles, after Eimeria maxima infection, between 2 B-complex congenic lines of Fayoumi chickens that display differences in disease resistance and innate immunity against avian coccidiosis using cDNA microarray. When compared with uninfected controls using a cutoff of >2.0-fold alteration (P < 0.05), M5.1 demonstrated altered expression o...
متن کاملImmune-related gene expression in two B-complex disparate genetically inbred Fayoumi chicken lines following Eimeria maxima infection.
To investigate the influence of genetic differences in the MHC on susceptibility to avian coccidiosis, M5.1 and M15.2 B-haplotype-disparate Fayoumi chickens were orally infected with live Eimeria maxima oocysts, and BW gain, fecal oocyst production, and expression of 14 immune-related genes were determined as parameters of protective immunity. Weight loss was reduced and fecal parasite numbers ...
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Two M5.1 and M15.2 B complex congenic lines of Fayoumi chickens were evaluated for body weight loss and faecal oocyst counts as parameters of avian coccidiosis. M5.1 chickens exhibited resistance to E. maxima compared with M15.2. To correlate the differential responses of the M5.1 and M15.2 lines to E. maxima infection with cellular immune responses, the expression levels of mRNAs encoding 14 i...
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The major histocompatibility (B) complex influence on resistance, susceptibility, and immunity to Eimeria tenella was examined in UCD B complex congenic chicken lines. In Experiment 1, 6-wk-old chicks from 12 UCD congenic lines were weighed and assigned to either challenge or control groups. The challenge group received a dose of 10,000 E. tenella oocysts. Response to challenge was evaluated by...
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Previously conducted studies using two chicken lines (A and B) show that line A birds have increased resistance to a number of bacterial and protozoan challenges and that heterophils isolated from line A birds are functionally more responsive. Furthermore, when stimulated with Toll-like receptor (TLR) agonists, heterophils from line A expressed a totally different cytokine and chemokine mRNA ex...
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ژورنال
عنوان ژورنال: Poultry Science
سال: 2009
ISSN: 0032-5791
DOI: 10.3382/ps.2009-00012